Ketamine

Ketamine infusion

Ketamine Infusion, is a medication primarily used for induction and maintenance of anesthesia. It induces dissociative anesthesia, a trance-like state providing pain relief, sedation, and amnesia.

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Ketamine was originally patented in Belgium in 1963 and was approved for use in humans by the U.S. Food and Drug Administration in 1970.

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Addiction To Ketamine

An addiction to Ketamine is difficult to overcome without help. Even when someone wants to stop using the drug, chemical changes in the brain make it nearly impossible to stop without professional help.

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Once an individual crosses into the addicted state, they spend their days feeling utterly detached from their surroundings and become incapable of leading a normal and productive life. They are usually cognitively impaired at this stage, with speech and memory both affected.

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Before taking this medicine

You should not be treated with ketamine if you are allergic to it, or if you have untreated or uncontrolled hypertension (high blood pressure).

Tell your doctor if you have ever had:

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Pharmacology of Ketamine

Ketamine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, and it blocks HCN1 receptors. However, at higher doses it may also bind to the opioid mu and sigma receptors. It disrupts the neurotransmitter (brain chemical) glutamate.

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Glutamate is involved with learning, memory, emotion, and pain recognition. It can exhibit sympathomimetic activity which can lead to rapid heart rate and elevated blood pressure.

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How is ketamine given?

Ketamine is injected into a muscle or a vein. A healthcare provider will give you this injection.

Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely.

You may feel strange or confused when you awake from anesthesia. Tell your caregivers if these feelings are severe or unpleasant.

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