Liquid ketamine, Ketamine is a rapid-acting general anesthetic and NMDA receptor antagonist used for induction of anesthesia diagnostic and surgical procedures typically in combination with a muscle relaxant.
Ketamine interacts with N-methyl-D-aspartate (NMDA) receptors, opioid receptors, monoaminergic receptors, muscarinic receptors and voltage sensitive Ca ion channels. Unlike other general anaesthetic agents, ketamine does not interact with GABA receptors.
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The Benefits of Ketamine Infusion Therapy
Ketamine is a hallucinogen or it contains an agent that produces hallucinations, a feeling of detachment from oneself. Though it is used as an anaesthetic and a reliever for intense pain, ketamine is not YET approved as a treatment for depression in spite of its amazing effects in treating different types of depression.
Studies show that there are still unreported cases about the effects of ketamine, and it still needs to satisfy the approving authority that ketamine is safe when it is administered with the right dose in the right route.
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Ketamine is highly associated with developing ulcerative cystitis, a form of panful bladder syndrome characterized by damage to the bladder’s tissues leading to chronic, recurring pelvic pain, with ulcers – red, bleeding patches – in the walls of the bladder. According to the Interstitial Cystitis Association, about 5 percent of people with interstitial cystitis, whether it is ulcerative or not, develop end-stage cystitis. This condition is a failure of the bladder, leading to an organ that is hard, extremely painful, and unable to hold urine
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Less Common Side Effects of Ketamine Treatment
- Hallucinations – it involves your senses; you see, feel, and hear things which seem real, but actually not.
- Dysphoric mood – a feeling of extreme sadness, irritability, and loss of interest in doing things you usually like. It is almost similar to a manic depressive state where suicidal thoughts are present. Notify the team in case of dysphoria happens.
- Mania – characterised by extreme euphoria, excessive and rapid thoughts, increased energy and talking too much. Ketamine infusion must be stopped immediately if mania is suspected.
- Liver damage – you will need a blood test every 6-8 months done by our doctors. An amount should be paid prior to the test.
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Also, esketamine is only part of the treatment for a person with depression. To date, it has only been shown to be effective when taken in combination with an oral antidepressant. For these reasons, esketamine is not considered a first-line treatment option for depression. It’s only prescribed for people with moderate to severe major depressive disorder who haven’t been helped by at least two other depression medications.
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